Category: ICP/CPP management

ICP/CPP management · Lund Concept · Neuroprotection

Review – Severe traumatic brain injury management and clinical outcome using the Lund concept

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In the reviewers own words: “This review covers the main principles of the Lund concept for treatment of severe traumatic brain injury. This is followed by a description of results of clinical studies in which this therapy or a modified version of the therapy has been used.” Published 2014 in Neuroscience by Koskinen et al. Access the abstract here. This… Continue reading Review – Severe traumatic brain injury management and clinical outcome using the Lund concept

Anaesthetic Agents · ICP/CPP management · Neuroprotection · Sedation

Cochrane Review – Barbiturates for acute traumatic brain injury

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The latest version of a Cochrane review of barbiturate therapy for ICP-management. “There is no evidence that barbiturate therapy in patients with acute severe head injury improves outcome. Barbiturate therapy results in a fall in blood pressure in one in four patients. This hypotensive effect will offset any ICP lowering effect on cerebral perfusion pressure”… Continue reading Cochrane Review – Barbiturates for acute traumatic brain injury

Decompressive Surgery · Surgical Measures · TBI General

DECRA trial – Decompressive Craniectomy in Diffuse Traumatic Brain Injury

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Important trial dealing with the contentious issue of decompressive craniectomy for diffuse traumatic brain injury. Cooper et al. New England Journal of Medicine 2011. “In adults with severe diffuse traumatic brain injury and refractory intracranial hypertension, early bifrontotemporoparietal decompressive craniectomy decreased intracranial pressure and the length of stay in the ICU but was associated with… Continue reading DECRA trial – Decompressive Craniectomy in Diffuse Traumatic Brain Injury

ICP/CPP management · Neuromonitoring · Prognostication

Intracranial hypertension and cerebral perfusion pressure: influence on neurological deterioration and outcome in severe head injury. The Executive Committee of the International Selfotel Trial

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Intracranial hypertension and cerebral perfusion pressure: influence on neurological deterioration and outcome in severe head injury. The Executive Committee of the International Selfotel Trial. J Neurosurg. 2000 Jan. Juul et al.