Category: Seizure Control

Neurocritical Care · Paediatrics · Pharmacology · Seizure Control

ConSEPT and EcLiPSE Trials: Levetiracetam Equal to Phenytoin in Efficacy for Convulsive Status Epilepticus in Children

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Just a quick update on two recent trials on pharmacological treatment for status epileptics in children: Both articles were published in the Lancet this spring. ConSEPT and EcLiPSE, both high-quality trials, found levetiracetam and phenytoin to be equally effective in seizure control and similar in safety profile. The findings were be remarkably consistent across the… Continue reading ConSEPT and EcLiPSE Trials: Levetiracetam Equal to Phenytoin in Efficacy for Convulsive Status Epilepticus in Children

Acute Cerebrovascular Conditions · Air Embolism · Aneurysm Surgery · Cervical Spine Surgery · General Topics · Haemodynamics · ICP/CPP management · Intracranial Surgery General · Ischaemic Stroke · Neuroanaesthesia · Neuromonitoring · Neurovascular Surgery · Perioperative Management · Sedation · Seizure Control · Subarachnoid Haemorrhage · Thoracolumbar Spine Surgery · US Guidelines · Ventilation and Oxygenation

SNACC – How to Handle Neuroanaesthetic Emergencies

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From our quality-focused colleagues at the Society for Neuroscience in Anesthesiology and Critical Care (SNACC) comes this set of guidelines for management of the most common emergencies encountered in neuroanaesthetic practice. Conceived with the purpose of addressing complex emergent issues in a concise, goal-directed and simplified manner, these cognitive aids are clear-cut and based on… Continue reading SNACC – How to Handle Neuroanaesthetic Emergencies

Neurocritical Care · Seizure Control · Thermoregulation

HYBERNATUS Trial: Hypothermia Not Associated With Better Outcomes in Status Epilepticus

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Results from the HYBERNATUS trial were just published in the New England Journal of Medicine by Legriel et al. This study recruited 270 patients with convulsive status epilepticus, randomized to either therapeutic hypothermia (32-34 C) or normothermia. All patients were intubated and on controlled ventilation when included. All received standard antiepileptic pharmacological treatment. Primary outcome… Continue reading HYBERNATUS Trial: Hypothermia Not Associated With Better Outcomes in Status Epilepticus