Neurocritical Care · Neuroprotection · Neurotrauma · Traumatic Brain Injury

Glycaemic Control Targets After Traumatic Brain Injury: A Systematic Review and Meta-analysis

Hermanides and colleagues recently reviewed all available evidence on blood glucose targets in the TBI patient. Read their finding in this article in Critical Care. When comparing strict glycaemic regimens with more liberal strategies they found no significant differences in patient-important outcomes, contrary to earlier findings. They did reveal an increased risk of hypoglycaemia, however.… Continue reading Glycaemic Control Targets After Traumatic Brain Injury: A Systematic Review and Meta-analysis

ICP/CPP management · Neurocritical Care · Neuroprotection · Neurotrauma · Thermoregulation · Traumatic Brain Injury

POLAR RCT – Don’t Worry, Thermoregulation Isn’t Dead Quite Yet

POLAR RCT is probably the most anticipated neurotrauma trial of the year and its findings were finally presented at this year’s ESICM congress in Paris. Before I comment on what POLAR RCT is all about, it’s worth taking some time to consider what this trial is NOT about. It does not deal specifically with TBI… Continue reading POLAR RCT – Don’t Worry, Thermoregulation Isn’t Dead Quite Yet

Acute Cerebrovascular Conditions · Basic Sciences & Physiology · Neurocritical Care · Neuromonitoring · Neuroprotection

Lactate Improves Cerebral Perfusion After Acute Brain Injury – Recent Clinical Trial in Crit Care Med

Lactate is well-known as an important energy substrate for brain tissue and plays a key role in neuroenergetics. Experimental data have shown that exogenous lactate administration may improve metabolism in injured brain cells, and possibly has neuroprotective properties. Till now there has been a paucity of human clinical studies on this subject. Carteron et al… Continue reading Lactate Improves Cerebral Perfusion After Acute Brain Injury – Recent Clinical Trial in Crit Care Med

Coagulopathy and Bleeding · Neurotrauma · Prognostication · Traumatic Brain Injury

Predictive Factors of Traumatic Intracranial Haemorrhage in Patients on Anti-platelet Agents

It’s been a lazy summer on our part, so it’s time to get back to business. And we’ll start off with this article by Moustafa et al, which was recently published in the Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. The authors deal with the issue of predicting risk of intracranial haemorrhage in TBI patients… Continue reading Predictive Factors of Traumatic Intracranial Haemorrhage in Patients on Anti-platelet Agents