Life in The Fast Lane´s take on the use of ketamine in traumatic brain injury. Nice summary of available literature. Sums it up succinctly for those who are still reluctant to use ketamine in this patient group. For more on the same subject, see this article on ketamine and ICP.
Retrospective cohort study by Patanwala and colleagues including 233 head injured patients that required RSI with either rocuronium or suxamethonium. The results reveal that sux was associated with increased mortality in the most severely injured subset, compared with roc. In patients with less severe injury there was no significant difference between the two NMBs. Interesting… Continue reading Roc or Sux in RSI of TBI Patients?
“The evidence of benefit of current strategies remains sparse.” Zwerus et al, The Netherlands. Current Opinions in Anesthesiology, 2015 Aug. Read abstract from the article here.
We can use ketamine in patients with traumatic brain injury… The ketamine effect on ICP in traumatic brain injury. Zeiler et al, Canada. Neurocritical Care, 2014 Aug. Access the abstract here.
The latest version of a Cochrane review of barbiturate therapy for ICP-management. “There is no evidence that barbiturate therapy in patients with acute severe head injury improves outcome. Barbiturate therapy results in a fall in blood pressure in one in four patients. This hypotensive effect will offset any ICP lowering effect on cerebral perfusion pressure”… Continue reading Cochrane Review – Barbiturates for acute traumatic brain injury