Anaesthetic Agents · ICP/CPP management · Neuroprotection · Sedation

Cochrane Review – Barbiturates for acute traumatic brain injury

The latest version of a Cochrane review of barbiturate therapy for ICP-management.

“There is no evidence that barbiturate therapy in patients with acute severe head injury improves outcome. Barbiturate therapy results in a fall in blood pressure in one in four patients. This hypotensive effect will offset any ICP lowering effect on cerebral perfusion pressure”

Read the full article by Roberts et al. (2012) here.


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