Neurocritical Care · Neuroprotection · Neurotrauma · Traumatic Brain Injury

Lancet Neurology – Special Issue Dedicated to TBI

I realise that this is old news by now, but I´ve somehow neglected to put out this excellent collection of articles on NeuroScand. The November issue of Lancet Neurology is dedicated in its entirety to traumatic brain injury and features a number of inspiring and thought-provoking editorials. Essential reading for the neurotrauma enthusiast.

Hypothermia · Neurocritical Care · Neuroprotection · Traumatic Brain Injury

TTM – New Guidelines from NCS

Targeted temperature management (TTM) as a neuroptotective strategy is applied in a number of scenarios; post-ROSC in cardiac arrest, neonatal asphyxia, traumatic brain injury, to name some. The Neurocritical Care Society have taken it upon themselves to formulate an evidence-based guideline to  the implementation and practical management of TTM in a number of settings. Although… Continue reading TTM – New Guidelines from NCS

Basic Sciences & Physiology · Neurocritical Care · Neuroprotection · Neurotrauma · Traumatic Brain Injury

Rethinking Neuroprotection in Severe Traumatic Brain Injury: Toward Bedside Neuroprotection

Summer is in its last month so it’s time to get back to the NeuroScand grind. And we do so with this article by Zoerle and colleagues (among whom we can count Dr. Nino Stocchetti), published in July in Frontiers in Neurology. “Rethinking Neuroprotection in Severe Traumatic Brain Injury: Toward Bedside Neuroprotection” starts off by… Continue reading Rethinking Neuroprotection in Severe Traumatic Brain Injury: Toward Bedside Neuroprotection

Hypothermia · Neurocritical Care · Seizure Control

HYBERNATUS Trial: Hypothermia Not Associated With Better Outcomes in Status Epilepticus

Results from the HYBERNATUS trial were just published in the New England Journal of Medicine by Legriel et al. This study recruited 270 patients with convulsive status epilepticus, randomized to either therapeutic hypothermia (32-34 C) or normothermia. All patients were intubated and on controlled ventilation when included. All received standard antiepileptic pharmacological treatment. Primary outcome… Continue reading HYBERNATUS Trial: Hypothermia Not Associated With Better Outcomes in Status Epilepticus

Hypothermia · ICP/CPP management · Neuroprotection · TBI General · Traumatic Brain Injury

Eurotherm 3235 Trial

The long-awaited Eurotherm trial was published in NEJM in autumn 2015. The premise of the study was to examine the impact of induced hypothermia on outcomes after traumatic brain injury. In a multi center randomized controlled trial patients were allocated to either therapeutic hypothermia (32-35 degrees) or the control group (standard care, normothermia). The study… Continue reading Eurotherm 3235 Trial