Neurocritical Care · Paediatrics · Pharmacology · Seizure Control

ConSEPT and EcLiPSE Trials: Levetiracetam Equal to Phenytoin in Efficacy for Convulsive Status Epilepticus in Children

Just a quick update on two recent trials on pharmacological treatment for status epileptics in children: Both articles were published in the Lancet this spring. ConSEPT and EcLiPSE, both high-quality trials, found levetiracetam and phenytoin to be equally effective in seizure control and similar in safety profile. The findings were be remarkably consistent across the… Continue reading ConSEPT and EcLiPSE Trials: Levetiracetam Equal to Phenytoin in Efficacy for Convulsive Status Epilepticus in Children

Fluid Management · Neuroanaesthesia · Osmotherapy · Paediatrics · Perioperative Management

Balanced Crystalloids Better Than Isotonic Saline for Craniotomy in Kids?

In this interesting trial by Lima and colleagues, with findings published recently in the Journal of Neurosurgical Anesthesiology, the authors compare normal saline (NS) with a balanced crystalloid as a maintenance fluid for elective tumour resection in paediatric patients. Their main endpoint was change in serum chloride from baseline to end of surgery. Perhaps unsurprisingly… Continue reading Balanced Crystalloids Better Than Isotonic Saline for Craniotomy in Kids?

Neurocritical Care · Neurotrauma · Paediatrics · Traumatic Brain Injury · US Guidelines

BTF Guidelines for Paediatric TBI 2019 – Finally Updated

In a long overdue update, the Brain Trauma Foundation have issued their recently revised guidelines for management of paediatric severe traumatic brain injury. We at neuroscand.com have yet to assess all of the recommendations yet, so expect more as we get through the whole document. At first glance, though, there seems to be little substantial… Continue reading BTF Guidelines for Paediatric TBI 2019 – Finally Updated