Just a quick update on two recent trials on pharmacological treatment for status epileptics in children: Both articles were published in the Lancet this spring. ConSEPT and EcLiPSE, both high-quality trials, found levetiracetam and phenytoin to be equally effective in seizure control and similar in safety profile. The findings were be remarkably consistent across the… Continue reading ConSEPT and EcLiPSE Trials: Levetiracetam Equal to Phenytoin in Efficacy for Convulsive Status Epilepticus in Children
In this interesting trial by Lima and colleagues, with findings published recently in the Journal of Neurosurgical Anesthesiology, the authors compare normal saline (NS) with a balanced crystalloid as a maintenance fluid for elective tumour resection in paediatric patients. Their main endpoint was change in serum chloride from baseline to end of surgery. Perhaps unsurprisingly… Continue reading Balanced Crystalloids Better Than Isotonic Saline for Craniotomy in Kids?
In a long overdue update, the Brain Trauma Foundation have issued their recently revised guidelines for management of paediatric severe traumatic brain injury. We at neuroscand.com have yet to assess all of the recommendations yet, so expect more as we get through the whole document. At first glance, though, there seems to be little substantial… Continue reading BTF Guidelines for Paediatric TBI 2019 – Finally Updated
Vanilla et al. Updated sept. 2014/ Literature review current through dec. 2015. Read this UpToDate article here.
“…evidence that cerebral perfusion pressure targets should be age specific.” Age-specific cerebral perfusion pressure thresholds and survival in children and adolescents with severe traumatic brain injury. Allen et al, USA. Pediatric Critical Care Medicine, 2014 Jan. Read the findings from this observational cohort study i full here.
“Cricoid pressure is contraindicated in patients with suspected cricotracheal injury, active vomiting, or unstable cervical spine injuries.” Cricoid pressure: indications and complications. Landsman, USA. Paediatic Anaesthesia, 2004 Jan. Abstract available here.
“The author recommends a controlled anesthesia induction by trained pediatric anesthesiologist with suitable equipment for the children considered at risk of pulmonary aspiration.” Rapid sequence induction has no use in pediatric anesthesia. Engelhard, UK. Paediatric Anaesthesia, 2015 Jan. Read the abstract from the review article here.