The Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC) recently released a superb article detailing the recommended treatment approach in TBI-patients with both cerebral tissue oximetry and ICP-monitoring. It provides an easy-to-follow and logical multi-tier algorithm for addressing various combinations of ICP/PbtO2 abnormalities. As such it offers a guidance document for clinical care that for the first time integrates the two most commonly used monitoring methods. Although the evidence for these two modalities in isolation is limited, there has been little in the way of prospective evaluation of multi-modal monitoring. This consensus document has established an excellent framework for just such future investigation.