Cardiovascular Conditions · Haemodynamics · Pharmacology · Systemic Effects of CNS Pathology · Traumatic Brain Injury

Beta-blockers and TBI

This is a subject that has been on our backburner for a while and it’s now due for a discussion on The use of beta-blockers in traumatic brain injury is nothing new. The indications have been largely centered on targeting and preventing paroxysmal sympathetic hyperactivity (PSH) and associated post-TBI autonomic phenomena. Please see our… Continue reading Beta-blockers and TBI

Basic Sciences & Physiology · Neurocritical Care · Neuroprotection · Neurotrauma · Traumatic Brain Injury

Rethinking Neuroprotection in Severe Traumatic Brain Injury: Toward Bedside Neuroprotection

Summer is in its last month so it’s time to get back to the NeuroScand grind. And we do so with this article by Zoerle and colleagues (among whom we can count Dr. Nino Stocchetti), published in July in Frontiers in Neurology. “Rethinking Neuroprotection in Severe Traumatic Brain Injury: Toward Bedside Neuroprotection” starts off by… Continue reading Rethinking Neuroprotection in Severe Traumatic Brain Injury: Toward Bedside Neuroprotection

Acute Cerebrovascular Conditions · EEG · Neuromonitoring · Subarachnoid Haemorrhage

EEG and Oxygenation in Acute Brain Injury

Really interesting article in the latest issue of JAMA Neurology: Specific EEG changes, known as periodic discharges (PDs), seem to be of value in predicting brain tissue hypoxia in vulnerable patients with acute brain injury. In this investigation, Witsch and colleagues included 90 patients with high-grade subarachnoid haemorrhage and monitored them with continuous EEG in addition to… Continue reading EEG and Oxygenation in Acute Brain Injury

Basic Sciences & Physiology · EEG · Neuromonitoring

Introduction to Intraoperative EEG Monitoring – A Starter´s Guide by ICETAP

Ivan came across this very useful and reasonably understandable introduction to EEG monitoring for anaesthetic use. It´s put together by the guys at ICETAP (International Consortium for EEG Training of Anesthesia Practitioners). It´s part of a series of tutorials on all things EEG for complete novices.

Basic Sciences & Physiology · Neuromonitoring

Assessment of cerebral autoregulation patterns with NIRS during pharmacological induced pressure changes

Moerman et al, Anesthesiology Aug 2015. Link to PubMed here. In this study, paradoxical changes in ScO2 after pharmacological-induced pressure changes occurred exclusively in patients with intact cerebral autoregulation, corroborating the hypothesis that these paradoxical responses might be attributable to a functional cerebral autoregulation.