Acute Cerebrovascular Conditions · discussions · Intracerebral Haemorrhage · Ischaemic Stroke · Neurocritical Care · Neuromonitoring · Neurotrauma · Subarachnoid Haemorrhage · Traumatic Brain Injury

Meyfroidt et al in ICM: Ten false beliefs in neurocritical care

Meyfroidt and colleagues recently published a commentary in Intensive Care Medicine addressing ten tenets in neurocritical care that merit debate. The article deals with the following ten statements: 1. Only neurointensivists should care about the brain. 2. Clinical examination of neurocritically ill patients is impossible. 3. We should no longer monitor ICP in traumatic brain… Continue reading Meyfroidt et al in ICM: Ten false beliefs in neurocritical care

Acute Cerebrovascular Conditions · Coagulopathy and Bleeding · Intracerebral Haemorrhage · Pharmacology · Subarachnoid Haemorrhage

TICH-2: No Benefit From TXA in ICH. What Now?

Tranexamic acid (TXA) has been held as something of a wonder drug. It’s cheap, largely demonstrated to be safe and has been given a role in a number of settings. The 2013 CRASH-2 trial showed improved survival in trauma with bleeding, and thus became one of the most widely cited publications in traumatology and emergency medicine. Several… Continue reading TICH-2: No Benefit From TXA in ICH. What Now?

Acute Cerebrovascular Conditions · Anaesthetic Agents · Ischaemic Stroke · Neuroanaesthesia · Sedation

Anaesthesia for Endovascular Treatment of Acute Ischaemic Stroke: Still Controversial?

A recently published review [1] by our Danish colleagues sums up the more recent trials on the subject of anaesthetic technique for endovascular treatments of ischaemic stroke. Previous publications, many of which are based largely on observational or retrospective data, have suggested harm from general anaesthesia (GA) for these procedures, when compared with conscious sedation… Continue reading Anaesthesia for Endovascular Treatment of Acute Ischaemic Stroke: Still Controversial?

Acute Cerebrovascular Conditions · European Guidelines · Fluid Management · Haemodynamics · Osmotherapy · Subarachnoid Haemorrhage · Traumatic Brain Injury

Fluid Therapy in Neurointensive Care patients – An ESICM Recommendation

Just published: the European Society of Intensive Care Medicine´s consensus document on fluid administration in the NICU. It covers all manner of neurocritical conditions and sums up the available evidence for various fluid therapy approaches. As expected there are few recommendations that aren´t already well established and by now fairly uncontroversial (multimodal monitoring, avoiding colloids,… Continue reading Fluid Therapy in Neurointensive Care patients – An ESICM Recommendation

Haemodynamics · Neurocritical Care · Neurotrauma · Pharmacology · Traumatic Brain Injury

Another Trial Suggesting Beta-blockers Are Beneficial in TBI: Time for an RCT!

We covered the subject of beta-blockade in traumatic brain injury last autumn in this article, where we summarised the increasing evidence that it seems to improve survival. A recently published trial (free full text) in the Journal of Trauma and Acute Care Surgery adds further credence to the role of beta-blockers in this patient group. This… Continue reading Another Trial Suggesting Beta-blockers Are Beneficial in TBI: Time for an RCT!

Neurocritical Care · Neuroprotection · Neurotrauma · Traumatic Brain Injury

Lancet Neurology – Special Issue Dedicated to TBI

I realise that this is old news by now, but I´ve somehow neglected to put out this excellent collection of articles on NeuroScand. The November issue of Lancet Neurology is dedicated in its entirety to traumatic brain injury and features a number of inspiring and thought-provoking editorials. Essential reading for the neurotrauma enthusiast.

Basic Sciences & Physiology · Haemodynamics · ICP/CPP management · Neurocritical Care · Neuromonitoring · Traumatic Brain Injury

Cerebral Autoregulation – What do we know?

We all recall the elegant curves that ostensibly show the neat relationship between mean  arterial blood pressure (or CPP) and cerebral blood flow. This relationship classically has its lower and upper limits, beyond which CBF will vary passively with the systemic pressure. Stay within these limits and all is good, the mantra goes. However, as… Continue reading Cerebral Autoregulation – What do we know?