Now more than three years old, but still an absolute landmark study and mandatory reading for anyone who cares for neurotrauma patients. Smallish trial but very well carried out and yielding some remarkable findings. A commonly cited article by Randy Chesnut and his group showing equipoise between an ICP-driven protocol and management determined by CT… Continue reading BEST TRIP – ICP vs. CT/clinical exam for TBI
Pressure-derived versus pressure wave amplitude-derived indices of cerebrovascular pressure reactivity in relation to early clinical state and 12-month outcome following aneurysmal subarachnoid haemorrhage. Abstract of original article by Eide et al. Published in the Journal of Neurosurgery 2012.
Routine intracranial pressure monitoring in acute coma (Cochrane 2015) A recent review of the available literature, pointing to the lack of sufficient evidence concerning the use of ICP monitoring in acute coma. Only one RCT has been conducted (see here) but this trial was questioned on the grounds of a disproportionally high mortality in both… Continue reading Cochrane review of routine ICP measurement in acute coma (2015)
Clinical review: neuromonitoring – an update. Review by Stocchetti et al. Crit Care. 2013.
Relationship of aggressive monitoring and treatment to improved outcomes in severe traumatic brain injury. Stein et al. J Neurosurg. 2010.
Intracranial hypertension and cerebral perfusion pressure: influence on neurological deterioration and outcome in severe head injury. The Executive Committee of the International Selfotel Trial. J Neurosurg. 2000 Jan. Juul et al.
Review article: Traumatic Intracranial Hypertension. A defining publication and a thorough and up-to-date review. N Engl J Med 2014 Nino Stocchetti, M.D., and Andrew I.R. Maas, M.D., Ph.D.
Prospective study revealing an improved outcome in TBI patients receiving more intensive care at specialized centres. Abstract at J Neurosurg Anesthesiol. 2011 Jul;23(3):198-205. Fuller et al.
New, freshly-released guidelines form the NICU at the Wessex Neurological Centre Wessex Neuro ICU Guidelines
A nice synopsis of neurocritical care of meningitis patients by the EMCrit/PulmCrit guys.
neuroscand.com 